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Patrick Galen Dempsey is an American actor and racecar driver who is best known for playing neurosurgeon Dr. Derek Shepherd in Grey's Anatomy. He is also known for his leading man romantic film roles, such as Enchanted. Dempsey has received nominations for a Primetime Emmy Award and two Golden Globe Awards, and was named as People's Sexiest Man Alive in 2023.
Dempsey started his career acting in films such as Can't Buy Me Love and Loverboy. He has since starred in several romantic comedy films such as Sweet Home Alabama , Made of Honor , Valentine's Day , and Bridget Jones's Baby. Dempsey has also taken dramatic roles in Outbreak , Scream 3 , Freedom Writers , Transformers: Dark of the Moon , Thanksgiving , and Ferrari. He starred in and produced Flypaper , and The Art of Racing in the Rain. In 2026, he began playing the main role of Angelo Doyle in the Fox crime drama Memory of a Killer....